STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (225 aa)    
Predicted Functional Partners:
PSM36_0438
Putative membrane protein.
       0.800
ileS
Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
  
 0.768
secF
Bifunctional preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
   
 0.632
PSM36_0436
DnaK suppressor protein; RNA polymerase-binding transcription factor DksA [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity.
  
    0.602
ppdK
Pyruvate, phosphate dikinase; ATP + pyruvate + phosphate <=> AMP + phosphoenolpyruvate + diphosphate; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family.
       0.493
PSM36_2997
Hypothetical protein; High confidence in function and specificity.
 
  
 0.493
PSM36_0354
Putative membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
  
 0.461
PSM36_3346
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; High confidence in function and specificity.
 
  
 0.458
PSM36_1966
RfbX; Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis]; High confidence in function and specificity.
 
     0.455
PSM36_0075
Hypothetical protein; High confidence in function and specificity.
 
   
 0.446
Your Current Organism:
Proteiniphilum saccharofermentans
NCBI taxonomy Id: 1642647
Other names: CECT 8610, DSM 28694, LMG 28299, LMG:28299, P. saccharofermentans, Proteiniphilum saccharofermentans Hahnke et al. 2016, Proteiniphilum sp. M3/6, strain M3/6
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