node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSM36_1013 | PSM36_1014 | PSM36_1013 | PSM36_1014 | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | 0.984 |
PSM36_1013 | PSM36_1044 | PSM36_1013 | PSM36_1044 | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | 0.404 |
PSM36_1014 | PSM36_1013 | PSM36_1014 | PSM36_1013 | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | 0.984 |
PSM36_1014 | PSM36_1044 | PSM36_1014 | PSM36_1044 | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | 0.400 |
PSM36_1043 | PSM36_1044 | PSM36_1043 | PSM36_1044 | Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]; High confidence in function and specificity. | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | 0.471 |
PSM36_1044 | PSM36_1013 | PSM36_1044 | PSM36_1013 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | 0.404 |
PSM36_1044 | PSM36_1014 | PSM36_1044 | PSM36_1014 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | ABC transporter; This family is related to the ABC-2 membrane transporter family pfam01061; High confidence in function and specificity. | 0.400 |
PSM36_1044 | PSM36_1043 | PSM36_1044 | PSM36_1043 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]; High confidence in function and specificity. | 0.471 |
PSM36_1044 | PSM36_1054 | PSM36_1044 | PSM36_1054 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | Ferredoxin-type protein NapF; High confidence in function and specificity. | 0.535 |
PSM36_1044 | PSM36_1055 | PSM36_1044 | PSM36_1055 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | Hypothetical protein; High confidence in function and specificity. | 0.459 |
PSM36_1044 | PSM36_1056 | PSM36_1044 | PSM36_1056 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors; High confidence in fun [...] | 0.455 |
PSM36_1044 | PSM36_1498 | PSM36_1044 | PSM36_1498 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | ABC-type multidrug transport system, permease component [Defense mechanisms]; High confidence in function and specificity. | 0.427 |
PSM36_1044 | PSM36_2537 | PSM36_1044 | PSM36_2537 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | O-succinylbenzoate-CoA ligase; O-succinylbenzoic acid-CoA synthase catalyzes the coenzyme A (CoA)-and ATP-dependent conversion of o-succinylbenzoic acid to o-succinylbenzoyl-CoA. The reaction is the fourth step of the biosynthesis pathway of menaquinone (vitamin K2). In certain bacteria, menaquinone is used during fumarate reduction in anaerobic respiration. In cyanobacteria, the product of the menaquinone pathway is phylloquinone (2-methyl-3-phytyl-1,4-naphthoquinone), a molecule used exclusively as an electron transfer cofactor in Photosystem 1. In green sulfur bacteria and heliobact [...] | 0.468 |
PSM36_1044 | ribBA | PSM36_1044 | PSM36_1739 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.439 |
PSM36_1044 | yngI | PSM36_1044 | PSM36_1944 | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | AMP-binding domain protein; High confidence in function and specificity. | 0.468 |
PSM36_1054 | PSM36_1044 | PSM36_1054 | PSM36_1044 | Ferredoxin-type protein NapF; High confidence in function and specificity. | This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin biosynthesis pathway, mtsD, part of the myxothiozol biosynthesis pathway; indC, part of the indigoidine biosynthesis pathway and tfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides; High confidence in function and specificity. | 0.535 |
PSM36_1054 | PSM36_1055 | PSM36_1054 | PSM36_1055 | Ferredoxin-type protein NapF; High confidence in function and specificity. | Hypothetical protein; High confidence in function and specificity. | 0.915 |
PSM36_1054 | PSM36_1056 | PSM36_1054 | PSM36_1056 | Ferredoxin-type protein NapF; High confidence in function and specificity. | TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors; High confidence in fun [...] | 0.589 |
PSM36_1054 | PSM36_2537 | PSM36_1054 | PSM36_2537 | Ferredoxin-type protein NapF; High confidence in function and specificity. | O-succinylbenzoate-CoA ligase; O-succinylbenzoic acid-CoA synthase catalyzes the coenzyme A (CoA)-and ATP-dependent conversion of o-succinylbenzoic acid to o-succinylbenzoyl-CoA. The reaction is the fourth step of the biosynthesis pathway of menaquinone (vitamin K2). In certain bacteria, menaquinone is used during fumarate reduction in anaerobic respiration. In cyanobacteria, the product of the menaquinone pathway is phylloquinone (2-methyl-3-phytyl-1,4-naphthoquinone), a molecule used exclusively as an electron transfer cofactor in Photosystem 1. In green sulfur bacteria and heliobact [...] | 0.519 |
PSM36_1054 | yngI | PSM36_1054 | PSM36_1944 | Ferredoxin-type protein NapF; High confidence in function and specificity. | AMP-binding domain protein; High confidence in function and specificity. | 0.519 |