STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSM36_1291The PI-PLC-like phosphodiesterases superfamily represents the catalytic domains of bacterial phosphatidylinositol-specific phospholipase C (PI-PLC, eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, glycerophosphodiester phosphodiesterases (GP-GDE, sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, from spider venom, SMases D-like proteins, and phospholipase D (PLD) from several pathogenic bacteria, as well as their uncharacterized homologs found in organisms ranging from bacteria and archaea to metazoans, plants, and fungi; High confidence in function and sp [...] (258 aa)    
Predicted Functional Partners:
PSM36_1599
This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Agrobacterium tumefaciens glycerophosphodiester phosphodiesterase (AtGDE, and its uncharacterized eukaryotic homolgoues. Members in this family shows high sequence similarity to Escherichia coli GP-GDE, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. AtGDE exists as a hexamer that is a trimer of dimers, which is unique among current known GDPD family members. However, it remains unclear if the hexamer plays [...]
  
  
  0.959
bglA
Beta-glucanase; Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)-and (1->4)-bonds; High confidence in function and specificity.
 
      0.899
PSM36_0129
Licheninase; Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)-and (1->4)-bonds; High confidence in function and specificity.
 
      0.887
PSM36_1290
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.691
PSM36_3447
Hypothetical protein; High confidence in function and specificity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.521
PSM36_3103
GDSL-like Lipase/Acylhydrolase family; High confidence in function and specificity.
 
    0.518
PSM36_0045
Hypothetical protein; High confidence in function and specificity.
  
 0.510
PSM36_1292
tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; High confidence in function and specificity.
       0.486
PSM36_2456
5'-nucleotidase, C-terminal domain; High confidence in function and specificity.
 
  
 0.436
PSM36_0030
Hypothetical protein; Family membership.
  
  
 0.416
Your Current Organism:
Proteiniphilum saccharofermentans
NCBI taxonomy Id: 1642647
Other names: CECT 8610, DSM 28694, LMG 28299, LMG:28299, P. saccharofermentans, Proteiniphilum saccharofermentans Hahnke et al. 2016, Proteiniphilum sp. M3/6, strain M3/6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.