STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSM36_2021This model describes a domain found typically in two or three proteins per genome in Cyanobacteria and Firmicutes, and sporadically in other genomes. One member is SpoIID of Bacillus subtilis. Another in B. subtilis is the C-terminal half of LytB, encoded immediately upstream of an amidase, the autolysin LytC, to which its N-terminus is homologous. Gene neighborhoods are not well conserved for members of this family, as many, such as SpoIID, are monocistronic. One early modelling-based study suggests a DNA-binding role for SpoIID, but the function of this domain is unknown. [Unknown fu [...] (440 aa)    
Predicted Functional Partners:
PSM36_2020
Putative Glycosyltransferase family 2; High confidence in function and specificity.
     0.990
PSM36_0698
Galactose-1-phosphate uridylyltransferase [Carbohydrate transport and metabolism]; High confidence in function and specificity.
 
     0.976
PSM36_2019
CBM6-CBM35-CBM36_like_2; Carbohydrate binding module family 6 (CBM6, family 6 CBM), also known as cellulose binding domain family VI (CBD VI), and related CBMs (CBM35 and CBM36). These are non-catalytic carbohydrate binding domains found in a range of enzymes that display activities against a diverse range of carbohydrate targets, including mannan, xylan, beta-glucans, cellulose, agarose, and arabinans. These domains facilitate the strong binding of the appended catalytic modules to their dedicated, insoluble substrates. Many of these CBMs are associated with glycoside hydrolase (GH) d [...]
 
  
 0.827
PSM36_1346
Hypothetical protein; High confidence in function and specificity.
  
     0.624
PSM36_2025
Major Facilitator Superfamily; High confidence in function and specificity.
 
     0.618
PSM36_2022
Transposase and inactivated derivatives.
       0.553
PSM36_3201
Hypothetical protein; High confidence in function and specificity.
  
     0.534
PSM36_1016
Outer membrane protein TolC [Cell wall/membrane/envelope biogenesis]; High confidence in function and specificity.
  
     0.531
PSM36_3380
Hypothetical protein; High confidence in function and specificity.
  
     0.491
PSM36_2018
Cellulose 1,4-beta-cellobiosidase; Glycoside hydrolase family 9 CAZY GH_9 comprises enzymes with several known activities including endoglucanase and cellobiohydrolase; High confidence in function and specificity.
 
     0.478
Your Current Organism:
Proteiniphilum saccharofermentans
NCBI taxonomy Id: 1642647
Other names: CECT 8610, DSM 28694, LMG 28299, LMG:28299, P. saccharofermentans, Proteiniphilum saccharofermentans Hahnke et al. 2016, Proteiniphilum sp. M3/6, strain M3/6
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