node1 | node2 | node1 annotation | node2 annotation | score |
PSM36_1396 | PSM36_1555 | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | acyl-CoA dehydrogenase; High confidence in function and specificity. | 0.708 |
PSM36_1396 | PSM36_2749 | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | 0.483 |
PSM36_1396 | PSM36_2958 | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | Hypothetical protein. | 0.505 |
PSM36_1555 | PSM36_1396 | acyl-CoA dehydrogenase; High confidence in function and specificity. | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | 0.708 |
PSM36_1555 | PSM36_2749 | acyl-CoA dehydrogenase; High confidence in function and specificity. | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | 0.961 |
PSM36_1555 | PSM36_2958 | acyl-CoA dehydrogenase; High confidence in function and specificity. | Hypothetical protein. | 0.638 |
PSM36_1555 | PSM36_3296 | acyl-CoA dehydrogenase; High confidence in function and specificity. | FAD/FMN-containing dehydrogenase [Energy production and conversion]; High confidence in function and specificity. | 0.470 |
PSM36_2749 | PSM36_1396 | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | 0.483 |
PSM36_2749 | PSM36_1555 | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | acyl-CoA dehydrogenase; High confidence in function and specificity. | 0.961 |
PSM36_2749 | PSM36_2958 | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | Hypothetical protein. | 0.847 |
PSM36_2749 | PSM36_3296 | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | FAD/FMN-containing dehydrogenase [Energy production and conversion]; High confidence in function and specificity. | 0.443 |
PSM36_2957 | PSM36_2958 | Putative secreted protein. | Hypothetical protein. | 0.575 |
PSM36_2957 | PSM36_2959 | Putative secreted protein. | Putative transposase OrfB. | 0.532 |
PSM36_2958 | PSM36_1396 | Hypothetical protein. | FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown; High confidence in function and specificity. | 0.505 |
PSM36_2958 | PSM36_1555 | Hypothetical protein. | acyl-CoA dehydrogenase; High confidence in function and specificity. | 0.638 |
PSM36_2958 | PSM36_2749 | Hypothetical protein. | 3-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. | 0.847 |
PSM36_2958 | PSM36_2957 | Hypothetical protein. | Putative secreted protein. | 0.575 |
PSM36_2958 | PSM36_2959 | Hypothetical protein. | Putative transposase OrfB. | 0.773 |
PSM36_2958 | PSM36_2960 | Hypothetical protein. | The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across [...] | 0.463 |
PSM36_2958 | PSM36_3296 | Hypothetical protein. | FAD/FMN-containing dehydrogenase [Energy production and conversion]; High confidence in function and specificity. | 0.527 |