H3G5V3_PHYRM protein (Phytophthora ramorum) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

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Score

H3G5V3_PHYRM

Uncharacterized protein. (148 aa)

Predicted Functional Partners:

H3GYA8_PHYRM

0.895

H3H571_PHYRM

0.818

H3H8R3_PHYRM

0.818

H3GMK0_PHYRM

0.790

H3HBH9_PHYRM

0.785

H3G763_PHYRM

0.763

H3H3F7_PHYRM

0.705

H3G568_PHYRM

0.692

H3HDH5_PHYRM

0.689

H3G5K7_PHYRM

0.686

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G568_PHYRM	H3G5V3_PHYRM	H3G568	H3G5V3	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.692
H3G568_PHYRM	H3GMK0_PHYRM	H3G568	H3GMK0	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.623
H3G568_PHYRM	H3GYA8_PHYRM	H3G568	H3GYA8	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein kinase domain-containing protein.	0.549
H3G5K7_PHYRM	H3G5V3_PHYRM	H3G5K7	H3G5V3	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.686
H3G5V3_PHYRM	H3G568_PHYRM	H3G5V3	H3G568	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.692
H3G5V3_PHYRM	H3G5K7_PHYRM	H3G5V3	H3G5K7	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.686
H3G5V3_PHYRM	H3G763_PHYRM	H3G5V3	H3G763	Uncharacterized protein.	Uncharacterized protein.	0.763
H3G5V3_PHYRM	H3GMK0_PHYRM	H3G5V3	H3GMK0	Uncharacterized protein.	Uncharacterized protein.	0.790
H3G5V3_PHYRM	H3GYA8_PHYRM	H3G5V3	H3GYA8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.895
H3G5V3_PHYRM	H3H3F7_PHYRM	H3G5V3	H3H3F7	Uncharacterized protein.	PCI domain-containing protein.	0.705
H3G5V3_PHYRM	H3H571_PHYRM	H3G5V3	H3H571	Uncharacterized protein.	Uncharacterized protein.	0.818
H3G5V3_PHYRM	H3H8R3_PHYRM	H3G5V3	H3H8R3	Uncharacterized protein.	Uncharacterized protein.	0.818
H3G5V3_PHYRM	H3HBH9_PHYRM	H3G5V3	H3HBH9	Uncharacterized protein.	Uncharacterized protein.	0.785
H3G5V3_PHYRM	H3HDH5_PHYRM	H3G5V3	H3HDH5	Uncharacterized protein.	Uncharacterized protein.	0.689
H3G763_PHYRM	H3G5V3_PHYRM	H3G763	H3G5V3	Uncharacterized protein.	Uncharacterized protein.	0.763
H3G763_PHYRM	H3GMK0_PHYRM	H3G763	H3GMK0	Uncharacterized protein.	Uncharacterized protein.	0.587
H3G763_PHYRM	H3H571_PHYRM	H3G763	H3H571	Uncharacterized protein.	Uncharacterized protein.	0.977
H3G763_PHYRM	H3H8R3_PHYRM	H3G763	H3H8R3	Uncharacterized protein.	Uncharacterized protein.	0.977
H3GMK0_PHYRM	H3G568_PHYRM	H3GMK0	H3G568	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.623
H3GMK0_PHYRM	H3G5V3_PHYRM	H3GMK0	H3G5V3	Uncharacterized protein.	Uncharacterized protein.	0.790

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.813

expected number of edges:

13

PPI enrichment p-value:

6.67e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000105

Histidine biosynthetic process

4 of 11

2.1

2.13

5.87e-05

GO:0008652

Cellular amino acid biosynthetic process

5 of 134

1.11

0.78

0.0067

GO:0006520

Cellular amino acid metabolic process

6 of 216

0.98

0.72

0.0051

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:29544475

(2018) Specific features of L-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphatemetal transport.

3 of 13

1.9

1.41

0.0015

PMID:30962820

(2019) Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum.

3 of 19

1.74

1.3

0.0020

PMID:29075239

(2017) Insight of Genus Corynebacterium: Ascertaining the Role of Pathogenic and Non-pathogenic Species.

2 of 14

1.7

0.69

0.0448

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1868

Mixed, incl. Polyol metabolic process, and DoxX

6 of 11

2.28

4.32

1.14e-09

CL:1871

Mixed, incl. DoxX, and RNA polymerase sigma-70 like

5 of 5

2.54

4.21

7.44e-09

CL:679

Histidine biosynthetic process

3 of 5

2.32

2.03

0.00014

CL:653

Aromatic amino acid family biosynthetic process, and Histidine biosynthetic process

4 of 21

1.82

1.86

0.00010

CL:585

Mixed, incl. Aromatic amino acid family biosynthetic process, and Histidine biosynthetic process

5 of 55

1.5

1.58

0.00010

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

bly00340

Histidine metabolism

4 of 34

1.61

1.53

0.00031

bly00400

Phenylalanine, tyrosine and tryptophan biosynthesis

3 of 26

1.6

1.2

0.0024

bly01230

Biosynthesis of amino acids

6 of 172

1.08

1.0

0.00031

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0368

Histidine biosynthesis

3 of 12

1.94

1.44

0.0014

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