STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3GGH5_PHYRMDNA helicase; Belongs to the MCM family. (1027 aa)    
Predicted Functional Partners:
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
  
0.999
H3G7X1_PHYRM
DNA helicase; Belongs to the MCM family.
  
0.999
H3GAS2_PHYRM
DNA helicase; Belongs to the MCM family.
  
0.999
H3GI57_PHYRM
Uncharacterized protein.
   
 0.998
H3GW97_PHYRM
CDT1 domain-containing protein.
   
 0.998
H3H580_PHYRM
Uncharacterized protein.
   
 0.998
H3G6C0_PHYRM
MCM domain-containing protein; Belongs to the MCM family.
  
0.995
H3G6I6_PHYRM
DNA helicase; Belongs to the MCM family.
   
0.995
H3G6Z8_PHYRM
MCM domain-containing protein; Belongs to the MCM family.
   
0.995
H3GAJ9_PHYRM
DNA helicase; Belongs to the MCM family.
  
0.995
Your Current Organism:
Phytophthora ramorum
NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death
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