H3GIL0_PHYRM protein (Phytophthora ramorum) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

H3GIL0_PHYRM

Uncharacterized protein. (295 aa)

Predicted Functional Partners:

H3GMK0_PHYRM

0.776

H3GYA8_PHYRM

0.648

H3GXH6_PHYRM

0.639

H3GCH5_PHYRM

0.574

H3GII9_PHYRM

0.574

H3H7W8_PHYRM

0.574

H3GGF6_PHYRM

0.566

H3GLX1_PHYRM

0.532

H3GAR2_PHYRM

0.496

H3GGC9_PHYRM

0.492

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3GAR2_PHYRM	H3GCH5_PHYRM	H3GAR2	H3GCH5	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	ANK_REP_REGION domain-containing protein.	0.500
H3GAR2_PHYRM	H3GGF6_PHYRM	H3GAR2	H3GGF6	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.438
H3GAR2_PHYRM	H3GII9_PHYRM	H3GAR2	H3GII9	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.500
H3GAR2_PHYRM	H3GIL0_PHYRM	H3GAR2	H3GIL0	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.496
H3GAR2_PHYRM	H3GMK0_PHYRM	H3GAR2	H3GMK0	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.730
H3GAR2_PHYRM	H3GXH6_PHYRM	H3GAR2	H3GXH6	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.862
H3GAR2_PHYRM	H3GYA8_PHYRM	H3GAR2	H3GYA8	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Protein kinase domain-containing protein.	0.596
H3GAR2_PHYRM	H3H7W8_PHYRM	H3GAR2	H3H7W8	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.500
H3GCH5_PHYRM	H3GAR2_PHYRM	H3GCH5	H3GAR2	ANK_REP_REGION domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.500
H3GCH5_PHYRM	H3GGF6_PHYRM	H3GCH5	H3GGF6	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.773
H3GCH5_PHYRM	H3GII9_PHYRM	H3GCH5	H3GII9	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.674
H3GCH5_PHYRM	H3GIL0_PHYRM	H3GCH5	H3GIL0	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.574
H3GCH5_PHYRM	H3GLX1_PHYRM	H3GCH5	H3GLX1	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.507
H3GCH5_PHYRM	H3GMK0_PHYRM	H3GCH5	H3GMK0	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.897
H3GCH5_PHYRM	H3GXH6_PHYRM	H3GCH5	H3GXH6	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.964
H3GCH5_PHYRM	H3GYA8_PHYRM	H3GCH5	H3GYA8	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.875
H3GCH5_PHYRM	H3H7W8_PHYRM	H3GCH5	H3H7W8	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.684
H3GGC9_PHYRM	H3GIL0_PHYRM	H3GGC9	H3GIL0	EGF_2 domain-containing protein.	Uncharacterized protein.	0.492
H3GGF6_PHYRM	H3GAR2_PHYRM	H3GGF6	H3GAR2	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.438
H3GGF6_PHYRM	H3GCH5_PHYRM	H3GGF6	H3GCH5	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.773

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Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.865

expected number of edges:

11

PPI enrichment p-value:

0.00479

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006325

Chromatin organization

7 of 181

1.11

0.97

0.00072

GO:0016571

Histone methylation

3 of 17

1.77

0.76

0.0339

GO:0031497

Chromatin assembly

4 of 75

1.25

0.6

0.0450

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035097

Histone methyltransferase complex

3 of 13

1.88

1.04

0.0094

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1126

Histone methylation, and Structural constituent of chromatin

9 of 28

2.03

5.49

7.82e-15

CL:1122

Mixed, incl. Histone methylation, and Structural constituent of chromatin

10 of 46

1.86

4.89

2.47e-15

CL:1128

Histone lysine methylation, and Structural constituent of chromatin

6 of 21

1.98

3.66

3.28e-09

CL:1129

Structural constituent of chromatin, and AWS domain

4 of 15

1.95

2.32

1.22e-05

CL:1172

Regulation of PTEN gene transcription, and JmjN domain

3 of 5

2.3

2.16

7.43e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04130

SNARE interactions in vesicular transport

3 of 24

1.62

1.02

0.0072

map04145

Phagosome

3 of 39

1.41

0.84

0.0138

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3214841

PKMTs methylate histone lysines

3 of 11

1.95

1.16

0.0057

MAP-4839726

Chromatin organization

4 of 58

1.36

0.88

0.0089

MAP-3247509

Chromatin modifying enzymes

4 of 58

1.36

0.88

0.0089

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000786

Nucleosome

3 of 11

1.95

1.14

0.0062

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