STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3GMD4_PHYRM2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (516 aa)    
Predicted Functional Partners:
H3G7Y0_PHYRM
DPH-type MB domain-containing protein.
   
 0.925
H3G8I7_PHYRM
Tr-type G domain-containing protein.
    
 0.912
H3G6U9_PHYRM
Tr-type G domain-containing protein.
    
 0.867
H3G917_PHYRM
Tr-type G domain-containing protein.
    
 0.867
H3G9L2_PHYRM
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
    
 0.867
H3GB03_PHYRM
TP_methylase domain-containing protein.
   
 0.777
H3GBC9_PHYRM
Uncharacterized protein.
   
 
 0.626
H3GMA5_PHYRM
RNA helicase.
   
   0.565
H3GAL1_PHYRM
WD_REPEATS_REGION domain-containing protein.
   
    0.557
H3GG11_PHYRM
Uncharacterized protein.
   
    0.512
Your Current Organism:
Phytophthora ramorum
NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death
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