H3GMF7_PHYRM protein (Phytophthora ramorum) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

H3GMF7_PHYRM

FYVE-type domain-containing protein. (834 aa)

Predicted Functional Partners:

H3HC09_PHYRM

0.776

H3HCS0_PHYRM

0.761

H3GS63_PHYRM

0.572

H3GVT8_PHYRM

0.572

H3GE86_PHYRM

0.502

H3HAU2_PHYRM

0.477

H3HCH5_PHYRM

0.477

H3G7D6_PHYRM

0.447

H3H1C0_PHYRM

0.441

H3GIG7_PHYRM

0.436

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G7D6_PHYRM	H3GIG7_PHYRM	H3G7D6	H3GIG7	Uncharacterized protein.	Uncharacterized protein.	0.986
H3G7D6_PHYRM	H3GMF7_PHYRM	H3G7D6	H3GMF7	Uncharacterized protein.	FYVE-type domain-containing protein.	0.447
H3GE86_PHYRM	H3GMF7_PHYRM	H3GE86	H3GMF7	Uncharacterized protein.	FYVE-type domain-containing protein.	0.502
H3GE86_PHYRM	H3GS63_PHYRM	H3GE86	H3GS63	Uncharacterized protein.	PI3K/PI4K domain-containing protein.	0.619
H3GE86_PHYRM	H3GVT8_PHYRM	H3GE86	H3GVT8	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.619
H3GE86_PHYRM	H3H1C0_PHYRM	H3GE86	H3H1C0	Uncharacterized protein.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.806
H3GE86_PHYRM	H3HAU2_PHYRM	H3GE86	H3HAU2	Uncharacterized protein.	SAC domain-containing protein.	0.704
H3GE86_PHYRM	H3HCH5_PHYRM	H3GE86	H3HCH5	Uncharacterized protein.	SAC domain-containing protein.	0.704
H3GIG7_PHYRM	H3G7D6_PHYRM	H3GIG7	H3G7D6	Uncharacterized protein.	Uncharacterized protein.	0.986
H3GIG7_PHYRM	H3GMF7_PHYRM	H3GIG7	H3GMF7	Uncharacterized protein.	FYVE-type domain-containing protein.	0.436
H3GMF7_PHYRM	H3G7D6_PHYRM	H3GMF7	H3G7D6	FYVE-type domain-containing protein.	Uncharacterized protein.	0.447
H3GMF7_PHYRM	H3GE86_PHYRM	H3GMF7	H3GE86	FYVE-type domain-containing protein.	Uncharacterized protein.	0.502
H3GMF7_PHYRM	H3GIG7_PHYRM	H3GMF7	H3GIG7	FYVE-type domain-containing protein.	Uncharacterized protein.	0.436
H3GMF7_PHYRM	H3GS63_PHYRM	H3GMF7	H3GS63	FYVE-type domain-containing protein.	PI3K/PI4K domain-containing protein.	0.572
H3GMF7_PHYRM	H3GVT8_PHYRM	H3GMF7	H3GVT8	FYVE-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.572
H3GMF7_PHYRM	H3H1C0_PHYRM	H3GMF7	H3H1C0	FYVE-type domain-containing protein.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.441
H3GMF7_PHYRM	H3HAU2_PHYRM	H3GMF7	H3HAU2	FYVE-type domain-containing protein.	SAC domain-containing protein.	0.477
H3GMF7_PHYRM	H3HC09_PHYRM	H3GMF7	H3HC09	FYVE-type domain-containing protein.	SAC domain-containing protein.	0.776
H3GMF7_PHYRM	H3HCH5_PHYRM	H3GMF7	H3HCH5	FYVE-type domain-containing protein.	SAC domain-containing protein.	0.477
H3GMF7_PHYRM	H3HCS0_PHYRM	H3GMF7	H3HCS0	FYVE-type domain-containing protein.	Uncharacterized protein.	0.761

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Network Stats

number of nodes:

10

number of edges:

19

average node degree:

3.8

avg. local clustering coefficient:

0.854

expected number of edges:

9

PPI enrichment p-value:

0.00352

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 107

1.67

4.11

8.96e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 54

1.97

6.23

4.86e-19

GO:0019843

rRNA binding

9 of 42

1.99

5.37

6.93e-15

GO:0003723

RNA binding

10 of 109

1.62

3.63

7.15e-14

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 58

1.94

6.13

2.00e-19

GO:0044391

Ribosomal subunit

5 of 15

2.19

3.89

6.52e-09

GO:0015935

Small ribosomal subunit

3 of 7

2.29

2.46

1.74e-05

GO:0015934

Large ribosomal subunit

2 of 8

2.06

1.32

0.0029

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1728

Ribosome, and Translation regulator activity

11 of 69

1.86

5.4

8.21e-18

CL:1730

rRNA-binding, and EFG, domain V

8 of 33

2.05

5.21

1.32e-13

CL:1734

rRNA-binding

7 of 28

2.06

4.66

1.08e-11

CL:1771

Mixed, incl. Small ribosomal subunit, and K Homology domain, type 2

4 of 8

2.36

3.24

4.63e-07

CL:1835

Translation elongation factor EF1B/ribosomal protein S6, and Structural constituent of ribosome

3 of 6

2.36

2.28

4.65e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 59

1.93

6.08

1.99e-19

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 43

1.98

5.3

9.13e-15

GOCC:0044391

Ribosomal subunit

6 of 19

2.16

4.37

3.16e-10

GOCC:0015935

Small ribosomal subunit

5 of 10

2.36

4.35

1.71e-09

GOCC:0022627

Cytosolic small ribosomal subunit

4 of 8

2.36

3.43

1.81e-07

GOCC:0043229

Intracellular organelle

11 of 417

1.08

1.5

1.91e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 56

1.96

6.22

1.94e-19

KW-0699

rRNA-binding

9 of 40

2.01

5.64

1.31e-15

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