H3GWW5_PHYRM protein (Phytophthora ramorum) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

H3GWW5_PHYRM

HECT domain-containing protein. (676 aa)

Predicted Functional Partners:

H3G789_PHYRM

0.658

H3G8V5_PHYRM

0.658

H3GV22_PHYRM

0.650

H3GYJ5_PHYRM

0.650

H3HC07_PHYRM

0.650

H3G8T9_PHYRM

0.565

H3GYH5_PHYRM

0.563

H3GPE9_PHYRM

0.540

H3GHW1_PHYRM

0.526

H3G6N1_PHYRM

0.519

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G6N1_PHYRM	H3G789_PHYRM	H3G6N1	H3G789	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.858
H3G6N1_PHYRM	H3G8T9_PHYRM	H3G6N1	H3G8T9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.888
H3G6N1_PHYRM	H3G8V5_PHYRM	H3G6N1	H3G8V5	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.858
H3G6N1_PHYRM	H3GHW1_PHYRM	H3G6N1	H3GHW1	UBIQUITIN_CONJUGAT_2 domain-containing protein.	E2_bind domain-containing protein.	0.740
H3G6N1_PHYRM	H3GPE9_PHYRM	H3G6N1	H3GPE9	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.728
H3G6N1_PHYRM	H3GV22_PHYRM	H3G6N1	H3GV22	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.727
H3G6N1_PHYRM	H3GWW5_PHYRM	H3G6N1	H3GWW5	UBIQUITIN_CONJUGAT_2 domain-containing protein.	HECT domain-containing protein.	0.519
H3G6N1_PHYRM	H3GYJ5_PHYRM	H3G6N1	H3GYJ5	UBIQUITIN_CONJUGAT_2 domain-containing protein.	HECT domain-containing protein.	0.960
H3G6N1_PHYRM	H3HC07_PHYRM	H3G6N1	H3HC07	UBIQUITIN_CONJUGAT_2 domain-containing protein.	HECT domain-containing protein.	0.960
H3G789_PHYRM	H3G6N1_PHYRM	H3G789	H3G6N1	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.858
H3G789_PHYRM	H3G8T9_PHYRM	H3G789	H3G8T9	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.994
H3G789_PHYRM	H3GHW1_PHYRM	H3G789	H3GHW1	Ubiquitin-like domain-containing protein.	E2_bind domain-containing protein.	0.837
H3G789_PHYRM	H3GPE9_PHYRM	H3G789	H3GPE9	Ubiquitin-like domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.837
H3G789_PHYRM	H3GV22_PHYRM	H3G789	H3GV22	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.999
H3G789_PHYRM	H3GWW5_PHYRM	H3G789	H3GWW5	Ubiquitin-like domain-containing protein.	HECT domain-containing protein.	0.658
H3G789_PHYRM	H3GYH5_PHYRM	H3G789	H3GYH5	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.858
H3G789_PHYRM	H3GYJ5_PHYRM	H3G789	H3GYJ5	Ubiquitin-like domain-containing protein.	HECT domain-containing protein.	0.736
H3G789_PHYRM	H3HC07_PHYRM	H3G789	H3HC07	Ubiquitin-like domain-containing protein.	HECT domain-containing protein.	0.736
H3G8T9_PHYRM	H3G6N1_PHYRM	H3G8T9	H3G6N1	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.888
H3G8T9_PHYRM	H3G789_PHYRM	H3G8T9	H3G789	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.994

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.788

expected number of edges:

11

PPI enrichment p-value:

2.85e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042558

Pteridine-containing compound metabolic process

3 of 10

1.68

1.2

0.0031

GO:0006431

methionyl-tRNA aminoacylation

2 of 2

2.21

1.09

0.0092

GO:0006520

Cellular amino acid metabolic process

6 of 86

1.05

0.94

0.00052

GO:0009086

Methionine biosynthetic process

2 of 5

1.81

0.89

0.0185

GO:0016070

RNA metabolic process

6 of 98

0.99

0.84

0.00098

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004825

methionine-tRNA ligase activity

2 of 2

2.21

0.82

0.0309

GO:0016741

Transferase activity, transferring one-carbon groups

4 of 34

1.28

0.71

0.0235

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

2 of 4

1.91

0.7

0.0473

GO:0016646

Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

2 of 6

1.73

0.68

0.0474

GO:0140101

Catalytic activity, acting on a tRNA

4 of 43

1.17

0.65

0.0276

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

7 of 178

0.8

0.63

0.0021

GO:0005622

Intracellular anatomical structure

11 of 747

0.37

0.31

0.0031

GO:0005737

Cytoplasm

10 of 672

0.38

0.3

0.0120

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:362

16S rRNA methyltransferase RsmB/F, and Formyl transferase

4 of 5

2.11

2.22

3.83e-05

CL:291

tRNA aminoacylation

3 of 13

1.57

1.03

0.0061

CL:79

Translation, and RNA biosynthetic process

7 of 147

0.88

0.71

0.0015

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cgo00670

One carbon pool by folate

5 of 9

1.95

2.85

5.07e-07

cgo00450

Selenocompound metabolism

3 of 6

1.91

1.59

0.00060

cgo00970

Aminoacyl-tRNA biosynthesis

4 of 27

1.38

1.24

0.00063

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0648

Protein biosynthesis

5 of 41

1.29

1.17

0.00060

KW-0030

Aminoacyl-tRNA synthetase

3 of 23

1.32

0.67

0.0333

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