H3GXF7_PHYRM protein (Phytophthora ramorum) - STRING interaction network

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query proteins and first shell of interactors

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

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[Homology]

Score

H3GXF7_PHYRM

Uncharacterized protein. (120 aa)

Predicted Functional Partners:

H3GCJ7_PHYRM

0.684

H3GGV1_PHYRM

0.645

H3GAQ1_PHYRM

0.626

H3H2I7_PHYRM

0.626

H3G880_PHYRM

0.605

H3G9N3_PHYRM

0.605

H3HDX5_PHYRM

0.605

H3G8T9_PHYRM

0.597

H3G789_PHYRM

0.595

H3G8V5_PHYRM

0.595

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G789_PHYRM	H3G880_PHYRM	H3G789	H3G880	Ubiquitin-like domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.835
H3G789_PHYRM	H3G8T9_PHYRM	H3G789	H3G8T9	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.994
H3G789_PHYRM	H3G9N3_PHYRM	H3G789	H3G9N3	Ubiquitin-like domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.835
H3G789_PHYRM	H3GAQ1_PHYRM	H3G789	H3GAQ1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.511
H3G789_PHYRM	H3GCJ7_PHYRM	H3G789	H3GCJ7	Ubiquitin-like domain-containing protein.	VEFS-Box domain-containing protein.	0.599
H3G789_PHYRM	H3GGV1_PHYRM	H3G789	H3GGV1	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.907
H3G789_PHYRM	H3GXF7_PHYRM	H3G789	H3GXF7	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.595
H3G789_PHYRM	H3H2I7_PHYRM	H3G789	H3H2I7	Ubiquitin-like domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.511
H3G789_PHYRM	H3HDX5_PHYRM	H3G789	H3HDX5	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.835
H3G880_PHYRM	H3G789_PHYRM	H3G880	H3G789	Histone H3; Belongs to the histone H3 family.	Ubiquitin-like domain-containing protein.	0.835
H3G880_PHYRM	H3G8T9_PHYRM	H3G880	H3G8T9	Histone H3; Belongs to the histone H3 family.	Ubiquitin-like domain-containing protein.	0.915
H3G880_PHYRM	H3G8V5_PHYRM	H3G880	H3G8V5	Histone H3; Belongs to the histone H3 family.	Ubiquitin-like domain-containing protein.	0.835
H3G880_PHYRM	H3GAQ1_PHYRM	H3G880	H3GAQ1	Histone H3; Belongs to the histone H3 family.	Uncharacterized protein.	0.813
H3G880_PHYRM	H3GCJ7_PHYRM	H3G880	H3GCJ7	Histone H3; Belongs to the histone H3 family.	VEFS-Box domain-containing protein.	0.858
H3G880_PHYRM	H3GGV1_PHYRM	H3G880	H3GGV1	Histone H3; Belongs to the histone H3 family.	Uncharacterized protein.	0.930
H3G880_PHYRM	H3GXF7_PHYRM	H3G880	H3GXF7	Histone H3; Belongs to the histone H3 family.	Uncharacterized protein.	0.605
H3G880_PHYRM	H3H2I7_PHYRM	H3G880	H3H2I7	Histone H3; Belongs to the histone H3 family.	WD_REPEATS_REGION domain-containing protein.	0.813
H3G8T9_PHYRM	H3G789_PHYRM	H3G8T9	H3G789	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.994
H3G8T9_PHYRM	H3G880_PHYRM	H3G8T9	H3G880	Ubiquitin-like domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.915
H3G8T9_PHYRM	H3G8V5_PHYRM	H3G8T9	H3G8V5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.994

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.809

expected number of edges:

22

PPI enrichment p-value:

0.00834

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0010467

Gene expression

10 of 175

1.05

1.27

1.82e-07

GO:0006351

Transcription, DNA-templated

4 of 27

1.46

1.14

0.0022

GO:0016070

RNA metabolic process

7 of 108

1.1

9.95e-05

GO:0006353

DNA-templated transcription, termination

2 of 4

1.99

0.81

0.0292

GO:0009059

Macromolecule biosynthetic process

7 of 187

0.87

0.68

0.0022

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003723

RNA binding

7 of 85

1.21

1.36

1.59e-05

GO:0003676

Nucleic acid binding

10 of 298

0.82

0.79

1.59e-05

GO:0003899

DNA-directed 5-3 RNA polymerase activity

2 of 5

1.89

0.77

0.0339

GO:0140098

Catalytic activity, acting on RNA

4 of 70

1.05

0.58

0.0321

GO:0140640

Catalytic activity, acting on a nucleic acid

5 of 138

0.85

0.49

0.0321

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:412

RNA degradation, and 3-5-exoribonuclease activity

3 of 6

1.99

1.67

0.00048

CL:53

Mixed, incl. Gene expression, and Nucleoside triphosphate biosynthetic process

10 of 187

1.02

1.21

1.60e-07

CL:62

Ribosomal protein, and Ribonucleoside triphosphate biosynthetic process

7 of 103

1.12

1.19

3.40e-05

CL:246

RNA polymerase

2 of 5

1.89

0.84

0.0247

CL:227

Mixed, incl. Ribosomal small subunit biogenesis, and PUA domain superfamily

2 of 7

1.75

0.73

0.0383

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ace03018

RNA degradation

4 of 10

1.89

2.09

3.58e-05

ace03020

RNA polymerase

2 of 4

1.99

0.92

0.0177

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0694

RNA-binding

6 of 63

1.27

1.34

6.85e-05

KW-0806

Transcription termination

2 of 3

2.12

0.88

0.0233

KW-0240

DNA-directed RNA polymerase

2 of 5

1.89

0.78

0.0325

KW-0548

Nucleotidyltransferase

3 of 34

1.24

0.65

0.0325

KW-0804

Transcription

4 of 78

1.0

0.56

0.0325

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003029

S1 domain

3 of 4

2.17

1.29

0.0037

IPR022967

RNA-binding domain, S1

3 of 5

2.07

1.27

0.0037

IPR012340

Nucleic acid-binding, OB-fold

4 of 29

1.43

1.0

0.0050

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00316

Ribosomal protein S1-like RNA-binding domain

3 of 5

2.07

1.67

0.00054

SM00322

K homology RNA-binding domain

2 of 5

1.89

0.84

0.0245

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