STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3GZ80_PHYRME3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2017 aa)    
Predicted Functional Partners:
H3GYJ5_PHYRM
HECT domain-containing protein.
   
 0.950
H3HC07_PHYRM
HECT domain-containing protein.
   
 0.950
H3G8P2_PHYRM
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.795
H3G8T9_PHYRM
Ubiquitin-like domain-containing protein.
   
 0.641
H3G789_PHYRM
Ubiquitin-like domain-containing protein.
    
  0.542
H3G8V5_PHYRM
Ubiquitin-like domain-containing protein.
    
  0.542
H3G8E0_PHYRM
ThiF domain-containing protein.
    
 0.532
H3GHW1_PHYRM
E2_bind domain-containing protein.
    
 0.532
H3GPE9_PHYRM
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
    
 0.532
H3GTH9_PHYRM
RING-CH-type domain-containing protein.
   
 0.448
Your Current Organism:
Phytophthora ramorum
NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death
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