node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | H3GI82_PHYRM | H3GAS1 | H3GI82 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.700 |
FEN1 | H3GS08_PHYRM | H3GAS1 | H3GS08 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | WD_REPEATS_REGION domain-containing protein. | 0.738 |
FEN1 | H3GTA2_PHYRM | H3GAS1 | H3GTA2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | VWFA domain-containing protein. | 0.606 |
FEN1 | H3H0W6_PHYRM | H3GAS1 | H3H0W6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly [ADP-ribose] polymerase. | 0.682 |
FEN1 | H3H4R1_PHYRM | H3GAS1 | H3H4R1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly [ADP-ribose] polymerase. | 0.682 |
FEN1 | H3H571_PHYRM | H3GAS1 | H3H571 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.605 |
FEN1 | H3HE74_PHYRM | H3GAS1 | H3HE74 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.666 |
H3GI82_PHYRM | FEN1 | H3GI82 | H3GAS1 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.700 |
H3GI82_PHYRM | H3H0W6_PHYRM | H3GI82 | H3H0W6 | Uncharacterized protein. | Poly [ADP-ribose] polymerase. | 0.675 |
H3GI82_PHYRM | H3H4R1_PHYRM | H3GI82 | H3H4R1 | Uncharacterized protein. | Poly [ADP-ribose] polymerase. | 0.675 |
H3GS08_PHYRM | FEN1 | H3GS08 | H3GAS1 | WD_REPEATS_REGION domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.738 |
H3GS08_PHYRM | H3GTA2_PHYRM | H3GS08 | H3GTA2 | WD_REPEATS_REGION domain-containing protein. | VWFA domain-containing protein. | 0.633 |
H3GS08_PHYRM | H3H0W6_PHYRM | H3GS08 | H3H0W6 | WD_REPEATS_REGION domain-containing protein. | Poly [ADP-ribose] polymerase. | 0.668 |
H3GS08_PHYRM | H3H4R1_PHYRM | H3GS08 | H3H4R1 | WD_REPEATS_REGION domain-containing protein. | Poly [ADP-ribose] polymerase. | 0.668 |
H3GS08_PHYRM | H3H571_PHYRM | H3GS08 | H3H571 | WD_REPEATS_REGION domain-containing protein. | Uncharacterized protein. | 0.881 |
H3GTA2_PHYRM | FEN1 | H3GTA2 | H3GAS1 | VWFA domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.606 |
H3GTA2_PHYRM | H3GS08_PHYRM | H3GTA2 | H3GS08 | VWFA domain-containing protein. | WD_REPEATS_REGION domain-containing protein. | 0.633 |
H3GTA2_PHYRM | H3GTC7_PHYRM | H3GTA2 | H3GTC7 | VWFA domain-containing protein. | SAP domain-containing protein. | 0.687 |
H3GTA2_PHYRM | H3H0W6_PHYRM | H3GTA2 | H3H0W6 | VWFA domain-containing protein. | Poly [ADP-ribose] polymerase. | 0.666 |
H3GTA2_PHYRM | H3H4R1_PHYRM | H3GTA2 | H3H4R1 | VWFA domain-containing protein. | Poly [ADP-ribose] polymerase. | 0.666 |