STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (134 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.925
AMS10949.1
Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.875
FtsA
Cell division protein FtsA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.778
AMS10468.1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.656
AMS11473.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.653
AMS11520.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.652
AMS10946.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.631
spoU
RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.623
raiA
Fis family transcriptional regulator; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
       0.614
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
     
 0.600
Your Current Organism:
Erysipelothrix rhusiopathiae
NCBI taxonomy Id: 1648
Other names: ATCC 19414, Bacillus insidiosus, Bacillus rhusiopathiae suis, Bacterium rhusiopathiae, CCUG 221, CIP 105957, DSM 5055, E. rhusiopathiae, Erysipelothrix erysipeloides, Erysipelothrix insidiosa, Erysipelothrix murisepticus, Erysipelothrix porci, NCTC 8163
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