STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)    
Predicted Functional Partners:
nifU
Iron-sulfur cluster assembly scaffold protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
thiI
tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.995
AMS10540.1
Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
   
 0.992
DltC
Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.841
ezrA
Septation ring formation regulator EzrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.837
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.785
nfuA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.778
iscR
[Fe-S]-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.774
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  
 0.619
trmU
tRNA(5-methylaminomethyl-2-thiouridine)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.529
Your Current Organism:
Erysipelothrix rhusiopathiae
NCBI taxonomy Id: 1648
Other names: ATCC 19414, Bacillus insidiosus, Bacillus rhusiopathiae suis, Bacterium rhusiopathiae, CCUG 221, CIP 105957, DSM 5055, E. rhusiopathiae, Erysipelothrix erysipeloides, Erysipelothrix insidiosa, Erysipelothrix murisepticus, Erysipelothrix porci, NCTC 8163
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