STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (282 aa)    
Predicted Functional Partners:
uppS
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
    
 0.928
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
    
 0.926
DgkA
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.921
folA2
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.554
AMS11718.1
Subtilase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.
       0.554
AMS11716.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.520
AMS11526.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.451
rsmA
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.430
pbpB
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.402
Your Current Organism:
Erysipelothrix rhusiopathiae
NCBI taxonomy Id: 1648
Other names: ATCC 19414, Bacillus insidiosus, Bacillus rhusiopathiae suis, Bacterium rhusiopathiae, CCUG 221, CIP 105957, DSM 5055, E. rhusiopathiae, Erysipelothrix erysipeloides, Erysipelothrix insidiosa, Erysipelothrix murisepticus, Erysipelothrix porci, NCTC 8163
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.