STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCC78815.1Na+/melibiose symporter. (465 aa)    
Predicted Functional Partners:
SCC78817.1
Protein of unknown function.
 
 
 0.976
SCC78813.1
Hypothetical protein.
 
  
 0.959
SCC78812.1
Hypothetical protein.
 
   
 0.897
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.647
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.647
SCC78820.1
Short-chain dehydrogenase.
 
    0.574
SCC78866.1
Isoquinoline 1-oxidoreductase, beta subunit.
   
    0.547
SCC78819.1
SnoaL-like domain-containing protein.
 
     0.546
nrdJ2
Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.545
lysK
lysyl-tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.499
Your Current Organism:
Salinarimonadaceae bacterium HL109
NCBI taxonomy Id: 1653334
Other names: Rhizobiales bacterium HL-109, S. bacterium HL-109, Salinarimonadaceae bacterium HL-109
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.