STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THC_0007ATPase AAA. (427 aa)    
Predicted Functional Partners:
THC_0746
Appr-1-p processing protein.
      0.910
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.800
THC_0003
CMP deaminase.
       0.787
THC_0005
Acetoacetate metabolism regulatory protein AtoC.
       0.773
THC_0006
Hypothetical protein.
       0.773
THC_1751
Primosome, DnaD subunit.
    0.730
THC_1783
DNA polymerase I.
  
  
 0.570
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.550
THC_0008
Pyruvate synthase.
  
    0.439
THC_0011
Pyruvate synthase.
  
    0.433
Your Current Organism:
Caldimicrobium thiodismutans
NCBI taxonomy Id: 1653476
Other names: C. thiodismutans, Caldimicrobium thiodismutans Kojima et al. 2016, DSM 29380, NBRC 110713, Thermodesulfobacteriaceae bacterium TF1, strain TF1
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