STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THC_0497Siroheme synthase. (226 aa)    
Predicted Functional Partners:
THC_0671
uroporphyrin-III C-methyltransferase.
 
 0.999
THC_0073
Cobalt-precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
   
 0.980
THC_0074
precorrin-3B C17-methyltransferase.
   
 0.966
THC_0072
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.940
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.933
THC_0079
Hypothetical protein.
  
  
 0.906
THC_1535
Transcriptional regulator.
    
  0.904
hemL
Glutamate-1-semialdehyde aminotransferase.
    
 0.866
THC_0498
Hypothetical protein.
       0.773
THC_0500
3-oxoacyl-ACP synthase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
   0.639
Your Current Organism:
Caldimicrobium thiodismutans
NCBI taxonomy Id: 1653476
Other names: C. thiodismutans, Caldimicrobium thiodismutans Kojima et al. 2016, DSM 29380, NBRC 110713, Thermodesulfobacteriaceae bacterium TF1, strain TF1
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