STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLO91954.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1010 aa)    
Predicted Functional Partners:
OLO91953.1
Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.952
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.938
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.930
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.930
OLO92175.1
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RNA polymerase beta chain family.
   
 0.925
OLO91215.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.877
OLO91950.1
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.875
OLO90105.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.867
OLO89476.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.854
OLO90981.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.825
Your Current Organism:
Actinomyces naeslundii
NCBI taxonomy Id: 1655
Other names: A. naeslundii, ATCC 12104, CCUG 18310, CCUG 2238, CCUG 32832, CCUG 35333, CDC W826, CIP 103128, DSM 43013, JCM 8349, NCTC 10301
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