STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLO89492.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)    
Predicted Functional Partners:
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
   0.702
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.640
OLO91446.1
NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.595
OLO89785.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.582
OLO89493.1
Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.571
OLO92034.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.558
OLO89563.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.558
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
   0.556
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
   0.553
OLO92072.1
Part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.508
Your Current Organism:
Actinomyces naeslundii
NCBI taxonomy Id: 1655
Other names: A. naeslundii, ATCC 12104, CCUG 18310, CCUG 2238, CCUG 32832, CCUG 35333, CDC W826, CIP 103128, DSM 43013, JCM 8349, NCTC 10301
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