STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLO89134.1Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (628 aa)    
Predicted Functional Partners:
OLO89697.1
Ketol-acid reductoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ketol-acid reductoisomerase family.
 
 
 0.996
OLO89691.1
Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.974
OLO89699.1
Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
  
 0.971
OLO89220.1
Threonine ammonia-lyase, biosynthetic; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.936
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
  
  
 0.932
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.928
OLO89698.1
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.908
OLO88818.1
2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.896
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.872
OLO89168.1
Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.843
Your Current Organism:
Actinomyces naeslundii
NCBI taxonomy Id: 1655
Other names: A. naeslundii, ATCC 12104, CCUG 18310, CCUG 2238, CCUG 32832, CCUG 35333, CDC W826, CIP 103128, DSM 43013, JCM 8349, NCTC 10301
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