STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase.
  
 
 0.938
purN
Phosphoribosylglycinamide formyltransferase 1.
  
 0.921
KND51398.1
Chemotaxis protein methyltransferase CheR.
   
 0.907
cphA
Cyanophycin synthetase.
  
 
 0.878
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the polypeptide deformylase family.
    
 0.871
KND51159.1
5-formyltetrahydrofolate cyclo-ligase.
  
 0.862
rnhA
Ribonuclease HI.
    
 0.846
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.841
ileS
isoleucyl-tRNA synthetase.
  
 
 0.836
argS-2
arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.819
Your Current Organism:
Parcubacteria bacterium C7867001
NCBI taxonomy Id: 1659195
Other names: P. bacterium C7867-001, Parcubacteria bacterium C7867-001
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