| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KSW12831.1 | arlS_2 | APY09_00220 | APY09_00210 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
| KSW12831.1 | crp | APY09_00220 | APY09_02145 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.820 |
| KSW12831.1 | folE | APY09_00220 | APY09_04135 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| KSW12831.1 | maf | APY09_00220 | APY09_00225 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.623 |
| KSW12831.1 | moaA | APY09_00220 | APY09_03625 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclic pyranopterin phosphate synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.810 |
| KSW12831.1 | ndkA | APY09_00220 | APY09_08585 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
| KSW12831.1 | nrdD | APY09_00220 | APY09_02040 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KSW12831.1 | pyk | APY09_00220 | APY09_08075 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
| KSW12831.1 | regX3 | APY09_00220 | APY09_00215 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.704 |
| KSW12831.1 | relA | APY09_00220 | APY09_08220 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
| arlS_2 | KSW12831.1 | APY09_00210 | APY09_00220 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
| arlS_2 | maf | APY09_00210 | APY09_00225 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.509 |
| arlS_2 | regX3 | APY09_00210 | APY09_00215 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| crp | KSW12831.1 | APY09_02145 | APY09_00220 | Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.820 |
| folE | KSW12831.1 | APY09_04135 | APY09_00220 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| folE | moaA | APY09_04135 | APY09_03625 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclic pyranopterin phosphate synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.906 |
| folE | ndkA | APY09_04135 | APY09_08585 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.833 |
| folE | nrdD | APY09_04135 | APY09_02040 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| folE | pyk | APY09_04135 | APY09_08075 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
| folE | relA | APY09_04135 | APY09_08220 | GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |