STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdRTranscriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (195 aa)    
Predicted Functional Partners:
KSW10630.1
Peptidoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.710
lexA
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.661
nrdE2
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.646
nrdF2
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
     
 0.551
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.531
nrdI
Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function.
      
 0.450
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.435
nrdH_1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.419
Your Current Organism:
Schaalia odontolytica
NCBI taxonomy Id: 1660
Other names: ATCC 17929, BCCM/LMG:18080, CCUG 20536, CIP 101124, DSM 19120, DSM 43760, JCM 14871, LMG 18080, LMG:18080, NCTC 9935, S. odontolytica
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