STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
devRLuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)    
Predicted Functional Partners:
AHU89209.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
AHU89891.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.877
AHU90324.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.872
nreB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.854
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
       0.817
AHU89216.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.817
mutM
5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.803
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
    0.802
AHU89217.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.799
AHU89219.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.799
Your Current Organism:
Trueperella pyogenes
NCBI taxonomy Id: 1661
Other names: ATCC 19411, Actinomyces pyogenes, Arcanibacterium pyogenes, Arcanobacterium pyogenes, Bacillus pyogenes, CCUG 13230, CIP 103129, Corynebacterium pyogenes, DSM 20630, LMG 16162, LMG:16162, NCTC 5224, T. pyogenes, strain C-100
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