pheA protein (Synechococcus sp. WH 8109) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

pheA

Prephenate dehydratase. (270 aa)

Predicted Functional Partners:

AHF62799.1

0.972

aspC

0.971

tyrA

0.939

hisC

0.914

panC

0.664

ribA/ribB

0.648

AHF62729.1

0.631

aroQ

0.597

glsF

0.588

aroC

0.579

Your Current Organism:

Synechococcus sp. WH 8109

NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHF62729.1	pheA	Syncc8109_0320	Syncc8109_0321	Hypothetical protein.	Prephenate dehydratase.	0.631
AHF62799.1	aroC	Syncc8109_0393	Syncc8109_0309	Prephenate dehydrogenase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.780
AHF62799.1	aspC	Syncc8109_0393	Syncc8109_1393	Prephenate dehydrogenase.	Aminotransferases class-I.	0.910
AHF62799.1	glsF	Syncc8109_0393	Syncc8109_0331	Prephenate dehydrogenase.	Glutamate synthase (NADPH).	0.583
AHF62799.1	hisC	Syncc8109_0393	Syncc8109_2559	Prephenate dehydrogenase.	Aminotransferases class-I.	0.967
AHF62799.1	panC	Syncc8109_0393	Syncc8109_0433	Prephenate dehydrogenase.	Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.	0.525
AHF62799.1	pheA	Syncc8109_0393	Syncc8109_0321	Prephenate dehydrogenase.	Prephenate dehydratase.	0.972
AHF62799.1	tyrA	Syncc8109_0393	Syncc8109_0640	Prephenate dehydrogenase.	Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.	0.597
aroC	AHF62799.1	Syncc8109_0309	Syncc8109_0393	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Prephenate dehydrogenase.	0.780
aroC	aroQ	Syncc8109_0309	Syncc8109_0554	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.	0.448
aroC	glsF	Syncc8109_0309	Syncc8109_0331	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Glutamate synthase (NADPH).	0.515
aroC	hisC	Syncc8109_0309	Syncc8109_2559	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Aminotransferases class-I.	0.567
aroC	pheA	Syncc8109_0309	Syncc8109_0321	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Prephenate dehydratase.	0.579
aroC	tyrA	Syncc8109_0309	Syncc8109_0640	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.	0.938
aroQ	aroC	Syncc8109_0554	Syncc8109_0309	3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.448
aroQ	pheA	Syncc8109_0554	Syncc8109_0321	3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.	Prephenate dehydratase.	0.597
aspC	AHF62799.1	Syncc8109_1393	Syncc8109_0393	Aminotransferases class-I.	Prephenate dehydrogenase.	0.910
aspC	glsF	Syncc8109_1393	Syncc8109_0331	Aminotransferases class-I.	Glutamate synthase (NADPH).	0.662
aspC	hisC	Syncc8109_1393	Syncc8109_2559	Aminotransferases class-I.	Aminotransferases class-I.	0.917
aspC	pheA	Syncc8109_1393	Syncc8109_0321	Aminotransferases class-I.	Prephenate dehydratase.	0.971