Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF64821.1 | glyA | Syncc8109_2514 | Syncc8109_0252 | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |
| AHF64821.1 | metA | Syncc8109_2514 | Syncc8109_0888 | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.912 |
| AHF64821.1 | metC | Syncc8109_2514 | Syncc8109_2098 | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | Putative cystathionine gamma-synthase. | 0.686 |
| AHF64821.1 | metH | Syncc8109_2514 | Syncc8109_1303 | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| AHF64821.1 | thrA | Syncc8109_2514 | Syncc8109_2052 | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine dehydrogenase. | 0.523 |
| cobC | glyA | Syncc8109_0771 | Syncc8109_0252 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| cobC | ilvA | Syncc8109_0771 | Syncc8109_1245 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.900 |
| cobC | metA | Syncc8109_0771 | Syncc8109_0888 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.800 |
| cobC | metH | Syncc8109_0771 | Syncc8109_1303 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.422 |
| cobC | spt | Syncc8109_0771 | Syncc8109_1473 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.905 |
| cobC | trpB | Syncc8109_0771 | Syncc8109_2528 | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cysD-2 | ilvA | Syncc8109_0889 | Syncc8109_1245 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.806 |
| cysD-2 | metA | Syncc8109_0889 | Syncc8109_0888 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.992 |
| cysD-2 | metC | Syncc8109_0889 | Syncc8109_2098 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Putative cystathionine gamma-synthase. | 0.940 |
| cysD-2 | metH | Syncc8109_0889 | Syncc8109_1303 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
| cysD-2 | thrA | Syncc8109_0889 | Syncc8109_2052 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Homoserine dehydrogenase. | 0.882 |
| glyA | AHF64821.1 | Syncc8109_0252 | Syncc8109_2514 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein; Belongs to the methylenetetrahydrofolate reductase family. | 0.943 |
| glyA | cobC | Syncc8109_0252 | Syncc8109_0771 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative alpha-ribazole-5'-P phosphatase; Belongs to the phosphoglycerate mutase family. | 0.939 |
| glyA | ilvA | Syncc8109_0252 | Syncc8109_1245 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.925 |
| glyA | metA | Syncc8109_0252 | Syncc8109_0888 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.800 |
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