| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF62586.1 | glcD | Syncc8109_0168 | Syncc8109_0725 | Putative glycolate oxidase subunit (Fe-S) protein. | Putative glycolate oxidase subunit GlcD. | 0.983 |
| AHF62586.1 | glcE | Syncc8109_0168 | Syncc8109_0166 | Putative glycolate oxidase subunit (Fe-S) protein. | Putative glycolate oxidase subunit GlcE. | 0.981 |
| AHF62586.1 | spt | Syncc8109_0168 | Syncc8109_1473 | Putative glycolate oxidase subunit (Fe-S) protein. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.905 |
| gcsH | gcvP | Syncc8109_2616 | Syncc8109_2615 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcsH | gcvT | Syncc8109_2616 | Syncc8109_2659 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcsH | glyA | Syncc8109_2616 | Syncc8109_0252 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
| gcsH | spt | Syncc8109_2616 | Syncc8109_1473 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.904 |
| gcvP | gcsH | Syncc8109_2615 | Syncc8109_2616 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP | gcvT | Syncc8109_2615 | Syncc8109_2659 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvP | glyA | Syncc8109_2615 | Syncc8109_0252 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.999 |
| gcvP | ilvA | Syncc8109_2615 | Syncc8109_1245 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.605 |
| gcvP | spt | Syncc8109_2615 | Syncc8109_1473 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.910 |
| gcvP | trpB | Syncc8109_2615 | Syncc8109_2528 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.536 |
| gcvT | gcsH | Syncc8109_2659 | Syncc8109_2616 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvT | gcvP | Syncc8109_2659 | Syncc8109_2615 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvT | glyA | Syncc8109_2659 | Syncc8109_0252 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
| gcvT | spt | Syncc8109_2659 | Syncc8109_1473 | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.910 |
| glcD | AHF62586.1 | Syncc8109_0725 | Syncc8109_0168 | Putative glycolate oxidase subunit GlcD. | Putative glycolate oxidase subunit (Fe-S) protein. | 0.983 |
| glcD | glcE | Syncc8109_0725 | Syncc8109_0166 | Putative glycolate oxidase subunit GlcD. | Putative glycolate oxidase subunit GlcE. | 0.974 |
| glcD | spt | Syncc8109_0725 | Syncc8109_1473 | Putative glycolate oxidase subunit GlcD. | Serine:pyruvate/alanine:glyoxylate aminotransferase. | 0.901 |
