STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (383 aa)    
Predicted Functional Partners:
kaiC
Putative circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.988
rpaA
Two component transcriptional regulator, winged helix family.
 
 0.983
AHF62552.1
Two component transcriptional regulator, winged helix family.
 
 
 0.837
rpaB
Two component transcriptional regulator, winged helix family.
 
 
 0.832
phoB
Two component transcriptional regulator, winged helix family.
 
 
 0.815
AHF64845.1
Two component transcriptional regulator, LuxR family.
 
 
 0.785
AHF63338.1
Two component transcriptional regulator, winged helix family.
  
 
 0.747
AHF64352.1
Hypothetical protein.
       0.595
AHF64179.1
Two component transcriptional regulator, winged helix family.
  
 
 0.507
AHF64005.1
Hypothetical protein.
  
     0.473
Your Current Organism:
Synechococcus sp. WH 8109
NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109
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