| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF64439.1 | accC | Syncc8109_2101 | Syncc8109_2347 | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.926 |
| AHF64439.1 | acs | Syncc8109_2101 | Syncc8109_1549 | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.930 |
| AHF64439.1 | leuA | Syncc8109_2101 | Syncc8109_2034 | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.925 |
| AHF64439.1 | leuB | Syncc8109_2101 | Syncc8109_0815 | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.415 |
| accC | AHF64439.1 | Syncc8109_2347 | Syncc8109_2101 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | 0.926 |
| accC | acs | Syncc8109_2347 | Syncc8109_1549 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
| accC | leuA | Syncc8109_2347 | Syncc8109_2034 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.964 |
| acs | AHF64439.1 | Syncc8109_1549 | Syncc8109_2101 | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate. | 0.930 |
| acs | accC | Syncc8109_1549 | Syncc8109_2347 | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.927 |
| acs | leuA | Syncc8109_1549 | Syncc8109_2034 | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.942 |
| ilvB | ilvD | Syncc8109_1985 | Syncc8109_1431 | Acetolactate synthase, large subunit, biosynthetic type. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.981 |
| ilvB | ilvE | Syncc8109_1985 | Syncc8109_1302 | Acetolactate synthase, large subunit, biosynthetic type. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.550 |
| ilvB | ilvN | Syncc8109_1985 | Syncc8109_2092 | Acetolactate synthase, large subunit, biosynthetic type. | Acetolactate synthase, small subunit. | 0.999 |
| ilvB | leuA | Syncc8109_1985 | Syncc8109_2034 | Acetolactate synthase, large subunit, biosynthetic type. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.937 |
| ilvB | leuB | Syncc8109_1985 | Syncc8109_0815 | Acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.966 |
| ilvB | leuC | Syncc8109_1985 | Syncc8109_0255 | Acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.576 |
| ilvB | leuD | Syncc8109_1985 | Syncc8109_0256 | Acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family. | 0.667 |
| ilvD | ilvB | Syncc8109_1431 | Syncc8109_1985 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase, large subunit, biosynthetic type. | 0.981 |
| ilvD | ilvE | Syncc8109_1431 | Syncc8109_1302 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.979 |
| ilvD | ilvN | Syncc8109_1431 | Syncc8109_2092 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase, small subunit. | 0.785 |