guaB protein (Synechococcus sp. WH 8109) - STRING interaction network

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Score

guaB

IMP dehydrogenase related 2. (387 aa)

Predicted Functional Partners:

guaA

0.982

purA

0.927

AHF62635.1

0.915

AHF64994.1

0.911

surE

0.902

purH

0.900

AHF64379.1

0.615

panC

0.607

trxA_1

0.553

ilvB

0.528

Your Current Organism:

Synechococcus sp. WH 8109

NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHF62635.1	AHF64994.1	Syncc8109_0222	Syncc8109_2688	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Glutamine amidotransferase class-I.	0.901
AHF62635.1	guaA	Syncc8109_0222	Syncc8109_0052	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.959
AHF62635.1	guaB	Syncc8109_0222	Syncc8109_2039	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	IMP dehydrogenase related 2.	0.915
AHF62635.1	purA	Syncc8109_0222	Syncc8109_0759	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.931
AHF62635.1	purH	Syncc8109_0222	Syncc8109_0240	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.929
AHF62635.1	surE	Syncc8109_0222	Syncc8109_1830	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.900
AHF64379.1	guaB	Syncc8109_2038	Syncc8109_2039	Hypothetical protein.	IMP dehydrogenase related 2.	0.615
AHF64994.1	AHF62635.1	Syncc8109_2688	Syncc8109_0222	Glutamine amidotransferase class-I.	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.901
AHF64994.1	guaA	Syncc8109_2688	Syncc8109_0052	Glutamine amidotransferase class-I.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.905
AHF64994.1	guaB	Syncc8109_2688	Syncc8109_2039	Glutamine amidotransferase class-I.	IMP dehydrogenase related 2.	0.911
AHF64994.1	panC	Syncc8109_2688	Syncc8109_0433	Glutamine amidotransferase class-I.	Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.	0.516
AHF64994.1	surE	Syncc8109_2688	Syncc8109_1830	Glutamine amidotransferase class-I.	Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.911
guaA	AHF62635.1	Syncc8109_0052	Syncc8109_0222	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.959
guaA	AHF64994.1	Syncc8109_0052	Syncc8109_2688	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Glutamine amidotransferase class-I.	0.905
guaA	guaB	Syncc8109_0052	Syncc8109_2039	GMP synthase; Catalyzes the synthesis of GMP from XMP.	IMP dehydrogenase related 2.	0.982
guaA	panC	Syncc8109_0052	Syncc8109_0433	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.	0.745
guaA	purA	Syncc8109_0052	Syncc8109_0759	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.878
guaA	purH	Syncc8109_0052	Syncc8109_0240	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.924
guaA	surE	Syncc8109_0052	Syncc8109_1830	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.964
guaB	AHF62635.1	Syncc8109_2039	Syncc8109_0222	IMP dehydrogenase related 2.	Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.915