Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metCPutative cystathionine gamma-synthase. (498 aa)    
Predicted Functional Partners:
metB
Cystathionine gamma-synthase.
 
  
 
0.983
cysK
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.979
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.969
cysK-2
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.949
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.941
cysD-2
O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
 
0.939
sir
Sulfite reductase, ferredoxin dependent; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.928
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.912
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.910
AHF64682.1
Cysteine desulfurase, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
     
 0.901
Your Current Organism:
Synechococcus sp. WH 8109
NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109
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