menF protein (Synechococcus sp. WH 8109) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

menF

Isochorismate synthase. (468 aa)

Predicted Functional Partners:

menD

0.989

AHF64930.1

0.905

AHF64853.1

0.874

trpE

0.867

aroC

0.855

menA

0.837

AHF62799.1

0.829

aspC

0.801

tyrA

0.800

hisC

0.800

Your Current Organism:

Synechococcus sp. WH 8109

NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHF62799.1	AHF64930.1	Syncc8109_0393	Syncc8109_2623	Prephenate dehydrogenase.	Hypothetical protein.	0.805
AHF62799.1	aroC	Syncc8109_0393	Syncc8109_0309	Prephenate dehydrogenase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.780
AHF62799.1	aspC	Syncc8109_0393	Syncc8109_1393	Prephenate dehydrogenase.	Aminotransferases class-I.	0.910
AHF62799.1	hisC	Syncc8109_0393	Syncc8109_2559	Prephenate dehydrogenase.	Aminotransferases class-I.	0.967
AHF62799.1	menF	Syncc8109_0393	Syncc8109_2549	Prephenate dehydrogenase.	Isochorismate synthase.	0.829
AHF62799.1	trpE	Syncc8109_0393	Syncc8109_0411	Prephenate dehydrogenase.	Anthranilate synthase.	0.505
AHF62799.1	tyrA	Syncc8109_0393	Syncc8109_0640	Prephenate dehydrogenase.	Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.	0.597
AHF64853.1	menA	Syncc8109_2546	Syncc8109_2548	O-succinylbenzoate--CoA ligase.	1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.	0.844
AHF64853.1	menD	Syncc8109_2546	Syncc8109_1566	O-succinylbenzoate--CoA ligase.	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.	0.828
AHF64853.1	menF	Syncc8109_2546	Syncc8109_2549	O-succinylbenzoate--CoA ligase.	Isochorismate synthase.	0.874
AHF64930.1	AHF62799.1	Syncc8109_2623	Syncc8109_0393	Hypothetical protein.	Prephenate dehydrogenase.	0.805
AHF64930.1	aroC	Syncc8109_2623	Syncc8109_0309	Hypothetical protein.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.801
AHF64930.1	aspC	Syncc8109_2623	Syncc8109_1393	Hypothetical protein.	Aminotransferases class-I.	0.800
AHF64930.1	hisC	Syncc8109_2623	Syncc8109_2559	Hypothetical protein.	Aminotransferases class-I.	0.800
AHF64930.1	menF	Syncc8109_2623	Syncc8109_2549	Hypothetical protein.	Isochorismate synthase.	0.905
AHF64930.1	trpE	Syncc8109_2623	Syncc8109_0411	Hypothetical protein.	Anthranilate synthase.	0.810
AHF64930.1	tyrA	Syncc8109_2623	Syncc8109_0640	Hypothetical protein.	Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.	0.800
aroC	AHF62799.1	Syncc8109_0309	Syncc8109_0393	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Prephenate dehydrogenase.	0.780
aroC	AHF64930.1	Syncc8109_0309	Syncc8109_2623	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Hypothetical protein.	0.801
aroC	hisC	Syncc8109_0309	Syncc8109_2559	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Aminotransferases class-I.	0.567