Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
cobAuroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (262 aa)    
Predicted Functional Partners:
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.994
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.976
AHF65029.1
Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.931
cobI/cbiL
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.929
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.926
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.887
sir
Sulfite reductase, ferredoxin dependent; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.875
AHF65026.1
Putative DNA mismatch repair protein, mutS fa.
  
  
 0.862
cobJ
precorrin-3B C17-methyltransferase.
  
 0.778
AHF62946.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.728
Your Current Organism:
Synechococcus sp. WH 8109
NCBI taxonomy Id: 166314
Other names: S. sp. WH 8109, Synechococcus sp. WH8109
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