Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA63030.1NAD(P)(+) transhydrogenase (AB-specific); KEGG: pmf:P9303_08601 putative nicotinamide nucleotide transhydrogenase, subunit alpha 1 (A1); PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal. (380 aa)    
Predicted Functional Partners:
EHA63032.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
EHA63031.1
KEGG: pmt:PMT1165 putative nicotinamide nucleotide transhydrogenase, subunit alpha 2 (A2).
 
  
 0.996
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.858
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.856
nadK-2
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.856
EHA60388.1
PFAM: Cytidylyltransferase; KEGG: pmt:PMT1460 nicotinic acid mononucleotide adenylyltransferase; Belongs to the NadD family.
     
 0.852
EHA63033.1
KEGG: pmf:P9303_08631 putative hydrolase of the alpha/beta-hydrolase fold.
       0.815
EHA58635.1
KEGG: amr:AM1_1309 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain.
     
  0.679
EHA60390.1
TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; KEGG: pmt:PMT1462 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family.
 
  
 
0.639
EHA63029.1
KEGG: pmf:P9303_08591 EF-1 guanine nucleotide exchange domain-containing protein.
       0.537
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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