STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (383 aa)    
Predicted Functional Partners:
kaiC
Putative circadian clock protein, KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.999
EHA61762.1
Two component transcriptional regulator, winged helix family; KEGG: pmf:P9303_26471 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
 
 0.982
EHA60233.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ana:alr4878 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain.
 
 
 0.955
EHA62448.1
Two component transcriptional regulator, winged helix family; KEGG: pmt:PMT0146 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
 
 0.906
EHA61768.1
Two component transcriptional regulator, winged helix family; KEGG: pmf:P9303_26531 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
 
 0.897
EHA60172.1
Two component transcriptional regulator, winged helix family; KEGG: sth:STH415 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
 
 0.888
EHA64309.1
Two component transcriptional regulator, winged helix family; KEGG: pmt:PMT1357 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
  
 0.887
EHA61814.1
KEGG: pmf:P9303_27181 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal.
 
 
 0.876
EHA63185.1
Two component transcriptional regulator, winged helix family; KEGG: pmf:P9303_09491 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, C-terminal; Signal transduction response regulator, receiver domain.
  
 0.875
EHA63634.1
KEGG: syf:Synpcc7942_1012 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal.
  
 0.872
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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