STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA63212.1SMC domain protein; PFAM: RecF/RecN/SMC; KEGG: pmf:P9303_13301 RecF protein:ABC transporter. (883 aa)    
Predicted Functional Partners:
EHA63213.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: pmf:P9303_13291 DNA repair exonuclease.
 
 0.999
EHA63467.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: pmj:P9211_07941 putative transcripton factor.
  
 0.990
EHA58636.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: amr:AM1_2519 hypothetical protein.
  
 0.990
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.976
EHA60243.1
TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: pmf:P9303_21731 superfamily II DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.
    
 0.971
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.938
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.938
EHA63639.1
FHA modulated glycosyl transferase/transpeptidase; KEGG: syf:Synpcc7942_2000 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Forkhead-associated (FHA) domain; Penicillin-binding protein, transpeptidase; SMART: Forkhead-associated (FHA) domain.
   
 0.797
EHA59333.1
KEGG: pmf:P9303_22951 Rad3-related DNA helicase.
    
  0.793
EHA63470.1
PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: pcu:pc0950 ATP-dependent DNA ligase.
   
 0.776
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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