STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
EHA63249.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa)    
Predicted Functional Partners:
EHA62302.1
KEGG: pmf:P9303_25191 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
 
 
 0.999
EHA64043.1
TIGRFAM: Dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; KEGG: pmf:P9303_18461 dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase.
 
 
 0.997
EHA64183.1
KEGG: pmt:PMT1227 putative GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
 
 
 0.997
EHA60101.1
FolC bifunctional protein; KEGG: pmt:PMT0330 putative bifunctional dihydrofolate/folylpolyglutamate synthase; TIGRFAM: Folylpolyglutamate synthetase; PFAM: Mur ligase, C-terminal.
 
 0.995
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.842
EHA62009.1
PFAM: Aminotransferase, class IV; KEGG: pmt:PMT2224 aminotransferase class-IV.
  
 
 0.801
EHA62008.1
Anthranilate synthase; KEGG: pmf:P9303_29681 putative p-aminobenzoate synthetase; PFAM: Chorismate binding, C-terminal.
 
 
 0.779
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.769
EHA59348.1
KEGG: pmf:P9303_22721 anthranilate synthase component I/chorismate-binding protein; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
 
 
 0.744
EHA63250.1
PFAM: Putative thiol-disulphide oxidoreductase DCC; KEGG: pmt:PMT1280 hypothetical protein.
       0.689
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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