STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA63338.1single-stranded-DNA-specific exonuclease RecJ; KEGG: pmf:P9303_14521 serine/threonine specific protein phosphatase; TIGRFAM: Bacterial RecJ exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1. (627 aa)    
Predicted Functional Partners:
EHA60243.1
TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: pmf:P9303_21731 superfamily II DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.
   
 0.843
EHA63337.1
Cl- channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; KEGG: pmt:PMT0762 chloride channel.
 
     0.817
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 
 0.669
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.604
EHA63335.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: pmf:P9303_14501 Fe-S-cluster oxidoreductase.
       0.603
EHA63333.1
Protein of unknown function UPF0016; PFAM: Uncharacterised protein family UPF0016; KEGG: pmt:PMT0765 hypothetical protein.
       0.571
EHA63334.1
Protein of unknown function UPF0016; PFAM: Uncharacterised protein family UPF0016; KEGG: pmt:PMT0764 hypothetical protein.
       0.571
EHA63339.1
KEGG: pmf:P9303_14541 putative CbbY-like protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase.
       0.570
EHA63340.1
KEGG: pmf:P9303_14551 hypothetical protein.
       0.554
EHA63336.1
Hypothetical protein.
       0.550
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.