Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (556 aa)    
Predicted Functional Partners:
EHA62964.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
EHA64319.1
Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: pmf:P9303_06371 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.999
EHA60634.1
PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; KEGG: pmt:PMT0165 RibD/RibG domain-containing protein.
  
 0.993
rpsB
KEGG: pmt:PMT0584 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; PFAM: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
 
 0.957
EHA62302.1
KEGG: pmf:P9303_25191 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
    
 0.951
EHA58611.1
Riboflavin biosynthesis protein RibF; SMART: Riboflavin kinase; TIGRFAM: Riboflavin kinase/FAD synthetase; KEGG: pmt:PMT0364 putative riboflavin kinase/FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family.
    
 0.951
EHA61918.1
CheW protein; KEGG: dak:DaAHT2_2535 response regulator receiver modulated CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein.
   
 0.948
EHA64183.1
KEGG: pmt:PMT1227 putative GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
 
 0.942
EHA60101.1
FolC bifunctional protein; KEGG: pmt:PMT0330 putative bifunctional dihydrofolate/folylpolyglutamate synthase; TIGRFAM: Folylpolyglutamate synthetase; PFAM: Mur ligase, C-terminal.
     
 0.939
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (20%) [HD]