Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EHA63533.1KEGG: pmy:Pmen_3664 glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (326 aa)    
Predicted Functional Partners:
EHA63447.1
TIGRFAM: Pyruvate kinase; KEGG: pmf:P9303_15431 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PEP-utilising enzyme, mobile domain; Belongs to the pyruvate kinase family.
  
 0.968
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.904
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
    
 0.720
EHA62965.1
KEGG: syn:slr0942 aldehyde reductase; PFAM: NADP-dependent oxidoreductase domain.
  
 0.705
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 
 0.698
EHA61864.1
2-hydroxy-3-oxopropionate reductase; KEGG: pmf:P9303_27951 putative 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding.
 
  
 0.682
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.677
EHA60204.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: pmt:PMT0220 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
     
 0.659
pgk
HAMAP: Phosphoglycerate kinase; KEGG: pmf:P9303_27971 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.653
EHA60101.1
FolC bifunctional protein; KEGG: pmt:PMT0330 putative bifunctional dihydrofolate/folylpolyglutamate synthase; TIGRFAM: Folylpolyglutamate synthetase; PFAM: Mur ligase, C-terminal.
     
  0.652
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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