Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EHA63588.1KEGG: pmi:PMT9312_0378 DNA-cytosine methyltransferase; TIGRFAM: C-5 cytosine methyltransferase; PFAM: C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (680 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.842
EHA63591.1
KEGG: pmi:PMT9312_0381 hypothetical protein.
    
 0.832
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.825
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
     
  0.825
EHA63587.1
DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.787
EHA63589.1
KEGG: pmc:P9515_04451 hypothetical protein.
       0.773
EHA63590.1
KEGG: pmb:A9601_04351 hypothetical protein.
       0.773
EHA63582.1
PFAM: Putative endonuclease, Z1 domain; KEGG: pmi:PMT9312_0373 endonuclease.
 
   
 0.772
EHA63583.1
KEGG: pmi:PMT9312_0374 hypothetical protein.
 
     0.729
EHA63592.1
TIGRFAM: RecB family nuclease, TM0106, putative; KEGG: pmh:P9215_04481 RecB family nuclease.
       0.532
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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