| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHA59278.1 | EHA60390.1 | Syn8016DRAFT_2648 | Syn8016DRAFT_2177 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; KEGG: pmt:PMT1462 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. | 0.560 |
| EHA59278.1 | EHA62283.1 | Syn8016DRAFT_2648 | Syn8016DRAFT_1578 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.487 |
| EHA59278.1 | EHA63270.1 | Syn8016DRAFT_2648 | Syn8016DRAFT_0311 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | PFAM: Glutamine synthetase, catalytic domain; KEGG: mar:MAE_09050 glutamate--ammonia ligase. | 0.964 |
| EHA59278.1 | EHA63643.1 | Syn8016DRAFT_2648 | Syn8016DRAFT_0684 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Serine--pyruvate transaminase; KEGG: pmf:P9303_16451 serine:pyruvate/alanine:glyoxylate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase. | 0.483 |
| EHA59278.1 | EHA63645.1 | Syn8016DRAFT_2648 | Syn8016DRAFT_0686 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | TIGRFAM: Glutamine synthetase type I; KEGG: pmt:PMT0601 glutamine synthetase, glutamate--ammonia ligase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp. | 0.964 |
| EHA59278.1 | murI | Syn8016DRAFT_2648 | Syn8016DRAFT_0662 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.950 |
| EHA59278.1 | purQ | Syn8016DRAFT_2648 | Syn8016DRAFT_0913 | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.882 |
| EHA60390.1 | EHA59278.1 | Syn8016DRAFT_2177 | Syn8016DRAFT_2648 | TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; KEGG: pmt:PMT1462 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | 0.560 |
| EHA60390.1 | EHA63643.1 | Syn8016DRAFT_2177 | Syn8016DRAFT_0684 | TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; KEGG: pmt:PMT1462 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. | Serine--pyruvate transaminase; KEGG: pmf:P9303_16451 serine:pyruvate/alanine:glyoxylate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase. | 0.849 |
| EHA60390.1 | murI | Syn8016DRAFT_2177 | Syn8016DRAFT_0662 | TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; KEGG: pmt:PMT1462 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; Belongs to the AlaDH/PNT family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.849 |
| EHA62283.1 | EHA59278.1 | Syn8016DRAFT_1578 | Syn8016DRAFT_2648 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | 0.487 |
| EHA62283.1 | murD | Syn8016DRAFT_1578 | Syn8016DRAFT_2149 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.536 |
| EHA62283.1 | murI | Syn8016DRAFT_1578 | Syn8016DRAFT_0662 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.902 |
| EHA63270.1 | EHA59278.1 | Syn8016DRAFT_0311 | Syn8016DRAFT_2648 | PFAM: Glutamine synthetase, catalytic domain; KEGG: mar:MAE_09050 glutamate--ammonia ligase. | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | 0.964 |
| EHA63270.1 | EHA63645.1 | Syn8016DRAFT_0311 | Syn8016DRAFT_0686 | PFAM: Glutamine synthetase, catalytic domain; KEGG: mar:MAE_09050 glutamate--ammonia ligase. | TIGRFAM: Glutamine synthetase type I; KEGG: pmt:PMT0601 glutamine synthetase, glutamate--ammonia ligase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp. | 0.904 |
| EHA63270.1 | murI | Syn8016DRAFT_0311 | Syn8016DRAFT_0662 | PFAM: Glutamine synthetase, catalytic domain; KEGG: mar:MAE_09050 glutamate--ammonia ligase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.852 |
| EHA63270.1 | purQ | Syn8016DRAFT_0311 | Syn8016DRAFT_0913 | PFAM: Glutamine synthetase, catalytic domain; KEGG: mar:MAE_09050 glutamate--ammonia ligase. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.849 |
| EHA63620.1 | murC | Syn8016DRAFT_0661 | Syn8016DRAFT_2850 | KEGG: pmf:P9303_18931 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.456 |
| EHA63620.1 | murI | Syn8016DRAFT_0661 | Syn8016DRAFT_0662 | KEGG: pmf:P9303_18931 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.856 |
| EHA63643.1 | EHA59278.1 | Syn8016DRAFT_0684 | Syn8016DRAFT_2648 | Serine--pyruvate transaminase; KEGG: pmf:P9303_16451 serine:pyruvate/alanine:glyoxylate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase. | KEGG: pmt:PMT1777 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | 0.483 |
