STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA63682.1DNA-directed DNA polymerase; KEGG: pmt:PMT0638 putative UmuC protein; PFAM: DNA-repair protein, UmuC-like. (424 aa)    
Predicted Functional Partners:
EHA59101.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.998
EHA63681.1
PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: pmf:P9303_16001 putative SOS mutagenesis protein UmuD; Belongs to the peptidase S24 family.
 
 0.996
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 0.926
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.917
EHA60091.1
Peptidylprolyl isomerase; KEGG: pmf:P9303_19721 FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type.
    
 
 0.881
EHA61763.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pmf:P9303_26481 DNA polymerase III subunit delta'.
   
 
 0.869
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.857
EHA60412.1
PFAM: Cell cycle protein; KEGG: pmf:P9303_04731 cell division protein FtsW; Belongs to the SEDS family.
   
 
 0.824
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
   
 
 0.824
EHA64154.1
CbbX protein; TIGRFAM: CbxX/CfqX, monofunctional; PFAM: ATPase, AAA-type, core; KEGG: pmf:P9303_08171 RuBisCo-expression protein CbbX; SMART: ATPase, AAA+ type, core.
     
 0.752
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.