EHA63784.1 protein (Synechococcus sp. WH 8016)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EHA63784.1

PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase. (297 aa)

Predicted Functional Partners:

EHA59101.1

0.913

polA

0.891

EHA63469.1

0.806

EHA64211.1

0.771

EHA61930.1

0.766

EHA59136.1

0.766

EHA63877.1

0.749

deaD

0.726

EHA63324.1

0.726

EHA59175.1

0.719

Your Current Organism:

Synechococcus sp. WH 8016

NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHA59101.1	EHA59136.1	Syn8016DRAFT_2824	Syn8016DRAFT_2859	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	0.841
EHA59101.1	EHA59175.1	Syn8016DRAFT_2824	Syn8016DRAFT_2898	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal.	0.906
EHA59101.1	EHA61930.1	Syn8016DRAFT_2824	Syn8016DRAFT_2002	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	SNF2-related protein; KEGG: pmt:PMT2158 SNF2/helicase domain-containing protein; PFAM: SNF2-related; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.	0.841
EHA59101.1	EHA63469.1	Syn8016DRAFT_2824	Syn8016DRAFT_0510	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	KEGG: mxa:MXAN_6073 hypothetical protein.	0.551
EHA59101.1	EHA63784.1	Syn8016DRAFT_2824	Syn8016DRAFT_0825	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase.	0.913
EHA59101.1	EHA63877.1	Syn8016DRAFT_2824	Syn8016DRAFT_0919	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Nuclear protein SET; PFAM: SET domain; KEGG: hoh:Hoch_1311 hypothetical protein.	0.676
EHA59101.1	polA	Syn8016DRAFT_2824	Syn8016DRAFT_0084	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.994
EHA59136.1	EHA59101.1	Syn8016DRAFT_2859	Syn8016DRAFT_2824	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.841
EHA59136.1	EHA63324.1	Syn8016DRAFT_2859	Syn8016DRAFT_0365	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	DEAD/DEAH box helicase domain protein; KEGG: aha:AHA_2353 putative ATP-dependent RNA helicase RhlE; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Belongs to the DEAD box helicase family.	0.826
EHA59136.1	EHA63469.1	Syn8016DRAFT_2859	Syn8016DRAFT_0510	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	KEGG: mxa:MXAN_6073 hypothetical protein.	0.780
EHA59136.1	EHA63784.1	Syn8016DRAFT_2859	Syn8016DRAFT_0825	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase.	0.766
EHA59136.1	EHA63877.1	Syn8016DRAFT_2859	Syn8016DRAFT_0919	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	Nuclear protein SET; PFAM: SET domain; KEGG: hoh:Hoch_1311 hypothetical protein.	0.891
EHA59136.1	EHA64211.1	Syn8016DRAFT_2859	Syn8016DRAFT_1254	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	TIGRFAM: Peptidase S26A, signal peptidase I; KEGG: pmf:P9303_07511 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.	0.719
EHA59136.1	deaD	Syn8016DRAFT_2859	Syn8016DRAFT_0202	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	0.826
EHA59136.1	polA	Syn8016DRAFT_2859	Syn8016DRAFT_0084	Helicase domain protein; KEGG: pmf:P9303_00371 superfamily II DNA/RNA helicases, SNF2 family protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.894
EHA59175.1	EHA59101.1	Syn8016DRAFT_2898	Syn8016DRAFT_2824	KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.906
EHA59175.1	EHA63469.1	Syn8016DRAFT_2898	Syn8016DRAFT_0510	KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal.	KEGG: mxa:MXAN_6073 hypothetical protein.	0.590
EHA59175.1	EHA63784.1	Syn8016DRAFT_2898	Syn8016DRAFT_0825	KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal.	PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase.	0.719
EHA59175.1	polA	Syn8016DRAFT_2898	Syn8016DRAFT_0084	KEGG: pmf:P9303_00881 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, core; SMART: DNA mismatch repair protein MutS, C-terminal.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.931
EHA61930.1	EHA59101.1	Syn8016DRAFT_2002	Syn8016DRAFT_2824	SNF2-related protein; KEGG: pmt:PMT2158 SNF2/helicase domain-containing protein; PFAM: SNF2-related; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.841