STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA63784.1PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase. (297 aa)    
Predicted Functional Partners:
EHA59101.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.990
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.951
EHA64252.1
Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth; KEGG: pmf:P9303_06981 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
 
 
 0.891
EHA61763.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pmf:P9303_26481 DNA polymerase III subunit delta'.
   
 0.873
EHA63212.1
SMC domain protein; PFAM: RecF/RecN/SMC; KEGG: pmf:P9303_13301 RecF protein:ABC transporter.
   
 0.776
EHA64211.1
TIGRFAM: Peptidase S26A, signal peptidase I; KEGG: pmf:P9303_07511 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
     
 0.772
EHA63027.1
Helicase domain protein; PFAM: Helicase, C-terminal; KEGG: pmf:P9303_08571 helicase domain-containing protein.
     
 0.717
EHA59333.1
KEGG: pmf:P9303_22951 Rad3-related DNA helicase.
   
 
 0.668
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
     
 0.619
EHA63785.1
PFAM: Virulence-associated E; KEGG: npu:Npun_F1665 virulence-associated E family protein.
       0.584
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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