close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA63864.1PFAM: Pentapeptide repeat; KEGG: pmf:P9303_16951 hypothetical protein. (172 aa)    
Predicted Functional Partners:
EHA63865.1
KEGG: pmf:P9303_16961 putative cobalamin synthesis protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobW; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal.
       0.800
EHA61868.1
PFAM: Pentapeptide repeat; KEGG: pmf:P9303_27891 hypothetical protein.
  
     0.755
EHA59395.1
PFAM: Pentapeptide repeat; KEGG: npu:Npun_F0732 pentapeptide repeat-containing protein.
  
     0.752
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.734
EHA63863.1
KEGG: pmt:PMT0558 putative uracil phosphoribosyltransferase.
       0.603
EHA63862.1
KEGG: pmf:P9303_16931 hypothetical protein.
       0.561
EHA60242.1
KEGG: pmf:P9303_21721 LysM domain-containing protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup.
    
 
 0.535
EHA62201.1
PFAM: Photosystem II PsbO, manganese-stabilising; KEGG: syf:Synpcc7942_0294 photosystem II manganese-stabilizing polypeptide.
  
     0.530
EHA61779.1
TIGRFAM: Phytoene desaturase; KEGG: pmt:PMT2004 phytoene desaturase; PFAM: Amine oxidase.
  
     0.463
ilvD
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: pmt:PMT0560 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
       0.444
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.