Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EHA64200.1TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: pmf:P9303_07631 cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR. (239 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.971
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.956
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.944
EHA63113.1
KEGG: pmf:P9303_09381 putative cobyrinic acid a,c-diamide synthase; TIGRFAM: Cobyrinic acid a,c-diamide synthase CbiA; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ-like glutamine amidotransferase.
 
 
 0.925
EHA63350.1
Cobalbumin biosynthesis protein; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; KEGG: pmt:PMT0749 putative cobinamide kinase.
 
 
 0.916
EHA63391.1
TIGRFAM: Cobaltochelatase, CobN subunit; KEGG: pmf:P9303_14911 cobalamin biosynthetic protein CobN; PFAM: CobN/magnesium chelatase.
  
  
 0.890
EHA62239.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: pmf:P9303_24541 cob(I)alamin adenosyltransferase.
  
  
 
0.889
EHA59340.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: pmf:P9303_22881 hypothetical protein.
  
  
 
0.886
EHA64198.1
Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: pmf:P9303_07651 phage integrase family.
       0.815
EHA64199.1
PFAM: Methyltransferase type 11; KEGG: pmt:PMT1242 methyltransferase.
       0.813
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
Server load: low (14%) [HD]