STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHA64252.1Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth; KEGG: pmf:P9303_06981 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. (274 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.995
EHA59101.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.966
EHA62482.1
TIGRFAM: Mutator MutT; PFAM: NUDIX hydrolase domain; HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; KEGG: pmf:P9303_01721 adenine glycosylase; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif.
    
 0.965
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.928
EHA63784.1
PFAM: DNA ligase, ATP-dependent, central; KEGG: bpm:BURPS1710b_1648 PBCV-1 DNA ligase.
 
 
 0.891
EHA63470.1
PFAM: DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, C-terminal; KEGG: pcu:pc0950 ATP-dependent DNA ligase.
  
 
 0.874
EHA61763.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: pmf:P9303_26481 DNA polymerase III subunit delta'.
   
 0.854
EHA63022.1
KEGG: pmf:P9303_08541 pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; Belongs to the pseudouridine synthase RsuA family.
  
    0.730
EHA63129.1
TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: pmt:PMT1069 putative pseudouridylate synthase specific to ribosomal small subunit; SMART: RNA-binding S4.
  
    0.730
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   0.723
Your Current Organism:
Synechococcus sp. WH 8016
NCBI taxonomy Id: 166318
Other names: S. sp. WH 8016, Synechococcus sp. WH8016
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